Clayton Andrews is a former left-handed pitcher in Major League Baseball. Andrews was taken in the third round of the 1996 amateur draft by the Toronto Blue Jays. His only major league appearances came with the Blue Jays in the 2000 season, where he racked up an ERA of 10.02 in twenty and two thirds innings. His record in eight games was 1-2 with one game finished. His lone major league win came on May 28 against the Detroit Tigers at Comerica Park where he pitched four hitless, scoreless innings of relief in a 12-7 Blue Jays victory. He was later traded to the Cincinnati Reds, but did not appear in any games with them.